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PRC Atlas
An Atlas of Phase Responses Curves for Circadian and Circatidal Rhythms
A Phase Response Curve (PRC) is a plot of phase-shifts as a function
of circadian phase of a stimulus such as light pulses, temperature pulses,
or pulses of drugs or chemicals. The PRC Atlas is a collection of hundreds
of published and unpublished PRCs. Compiling the Atlas was initiated by Dr.
Colin
Pittendrigh (1919-1996,
Memorial) and Dr.
Pat DeCoursey (University of South Carolina) in 1977. We present here
the latest version of the Atlas compiled by Carl Johnson in 1990s.
Acknowledgements
The idea of compiling and standardizing all published PRCs into a single
volume originated with Dr. Colin Pittendrigh. He decidedthat it would be a
good project for the participants of the 1977 Clocks Workshop, held at Hopkins
Marine Station, Pacific Grove, California. He then enlisted the aid of Dr.
Pat DeCoursey to direct the endeavor. About 40 PRCs were standardized that
summer under her guidance. Dr. Pittendrigh then asked me to complete the
task, which I have accomplished with the help of many other people. In
particular I thank the following: Evelyn Parker for compiling the Drosophila
pseudoobscura PRCs, Grace Monty and Sharon Pagni for typing/word
processing, Jayati Kesavan and Bill Crouch for plotting and proof-reading,
and Dr. Van Gooch for putting the PRC Atlas on computer diskettes. I also
thank numerous other people for advice and encouragement- in particular,
Drs. Terry Page and Pat DeCoursey.
Carl Johnson
Before downloading the PRC Atlas, if you would like to know more about PRCs,
please take a look at the following articles.
Hardcopy version of PRC Atlas
Computer software versions of PRC Atlas
The PRC Atlas was laboriously converted to computer files by Dr. Van
Gooch (University of Minnesota). These computer files are the basis of
two user-friendly computer program versions of the PRC Atlas: one for PCs,
written by Dr. Mark Stokes (Monash University) and the other for
Macintoshs by
Dr. Takao Kondo (Nagoya University).
Text Format of the Data
The text format of the data can be downloaded from
Dr. Gooch's web site.
Microsoft Excel version
The PRC Atlas for MS- Excel was developed by Dr. Mark A. Stokes.
The program may be used on any PC compatible computer using a minimum
of DOS 5.0 with Windows 3.x and Microsoft Excel 5. It is best run with
Microsoft Excel 7. on Windows system. The program is designed to run
on 800x600 SVGA monitors (file: prc6x8.xls), or monitors with a resolution
equal to or greater than 1024x768 (file: prcatlas.xls).
[Download Excel version]
* This version may also work with MS-Excel on MacOS but absolutely
no guarantee. If you wanna try, please click
here.
Macintosh HyperCard version
The HyperCard version of the PRC Atlas was developed
by Dr. Takao Kondo to facilitate the retrieval of data from the PRC Atlas.
It may work on HyperCard ver 2 or later used with Macintosh System 6.05
or later. [Download
HyperCard version]
Interactive version of PRC Atlas
An interactive version (web version) of the Atlas is currently under development and will be available on this site.
Comments on the Standardized Format
References
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